There are a lot of different compounds being investigated – and in some cases, already used – for their potential effect on longevity. It makes sense that a company with a name like Combilytics (a portmanteau of “combination” and “senolytics”) would try to mix a lot of them together to create an exciting new supplement, EternLFX (https://longevity.technology/news/combilytics-taking-a-combined-approach-to-senescence/).
If you’ve spent any time reading about longevity science before, you’ll probably be familiar with the concept of senescent cells. For those who missed those articles or have forgotten, senescent cells are old and tired, but they just won’t die. Instead, they hang around, not doing the jobs they are supposed to do while releasing all kinds of toxins that can damage other parts of your body. No wonder they’re sometimes nicknamed “zombie cells.” They’re a major force behind many age-related diseases.
You can keep your overall number of senescent cells down by living well: diet, exercise and all those old favorites. Some are unavoidable, though, especially as we grow older. Senolytics are molecules that may be able to destroy senescent cells, or at least stop them from releasing their toxins, but not every senolytic works with every cell. That means developing new senolytics is an important area of research.
EternLFX contains quercetin, usually found in onions and apples, and fisetin, responsible for the red color of strawberries. Both seem to work on epithelial and adipose tissue (skin and fat). There are also six other ingredients: green tea extract EGCG, ginger root extract, black pepper fruit extract, grapefruit extract, licorice fruit extract and bromelain. Together, they should make EternLFX more bioavailable.
The strength of EternLFX isn’t just in its ingredients list; it’s also in its dosing program. You probably know that products work differently depending on a range of factors, such as weight, age and sex. Not all products are tested on every possible variation, which can lead to awkward moments if you’re not part of the standard test group.
EternLFX has a meticulously developed dosing program that takes many of these variables into account, along with active and inactive cycles, so you know how much to take depending on your unique biology.
You won’t need a prescription for EternLFX, but like many senolytics, it’s still a relatively new category of supplement that isn’t yet widely available. Combilytics certainly has lots of potential for the future.
